CHILDREN INPATIENTS: PRECISION DOSE EVALUATIONIN HOSPITAL KRATON PEKALONGAN PERIOD OF 2018

Abstract

Abstract

Background The infants and children was a period of growth. Children are not small adults. The medicines for children is a special case related to differences of organ development, the enzyme system responsible, metabolism and excretion. It is important for pediatrics is the optimal dose, dosing regimen can not be reduced simply based on weight or body surface area pediatric patients extrapolation of data obtained from adult patients. Objectives The aim of this study was to determine the accuracy of the dose of the drug in childreninpatients in the rose room KratonHospital Pekalongan in periode2018.Methods This research method is descriptive with inpatient medical record data retrieval child in the room rose in 2018. 1290 population of medical records by sampling 10% of the population in order to obtain results of 130 samples. The age inclusion was one month until 18 years that medical records are complete and clear and exclusion criteria that patients who died while undergoing treatment. Results This study suggested that the children not appropriate dose of the drug with a percentage of 27% and the right dose 73%.Conclusion The doctors and pharmacists can improve their colaboration about the pharmacodinamics and pharmacokinetics to get the best the rational dose adjusment. The efficacy and safety of drugs also should be concern.

Keywords: Child, precision dose, hospital, inpatients